Rogue Assassination Rotation & Opener

First ~12 casts of actual top-ranked kills. Trinkets and racials vary by setup; the skill order is what to copy.

1 Garrote 2 Fan of Knives 3 Rupture 4 Garrote 5 Mutilate 6 Mutilate 7 Mutilate 8 Mutilate 9 Envenom 10 Voracious Heart of Ula'tekOff-GCD 11 Deathmark 12 Kingsbane 13 VanishOff-GCD 14 Envenom 15 Mutilate

1 Garrote 2 Mutilate 3 Mutilate 4 Rupture 5 Mutilate 6 Mutilate 7 Mutilate 8 Mutilate 9 Envenom 10 Voracious Heart of Ula'tekOff-GCD 11 Deathmark 12 Kingsbane 13 Envenom 14 VanishOff-GCD 15 Garrote

1 Garrote 2 Mutilate 3 Mutilate 4 Rupture 5 Mutilate 6 Mutilate 7 Mutilate 8 Mutilate 9 Envenom 10 Roar of RezanOff-GCD 11 Voracious Heart of Ula'tekOff-GCD 12 Deathmark 13 Kingsbane 14 Envenom 15 Mutilate

Ability	Top-player CPM
Mutilate	20.2
Envenom	12.3
Garrote	3.0
Rupture	2.4
Fan of Knives	1.6
Crimson Tempest	1.5
FeintOff-GCD	1.0
Kingsbane	1.0
ShadowstepOff-GCD	0.7
Deathmark	0.6
VanishOff-GCD	0.6
Thistle TeaOff-GCD	0.6
Crimson Vial	0.4
SprintOff-GCD	0.4

CPM = median casts per minute across the sampled top kills. If you're far below on a core ability, that's usually the first thing to fix.

First ~12 casts after the pull starts, taken from actual top key runs: the AoE opener is the first pack of the run, the single-target opener is the first boss. Trinkets and racials vary by setup; the skill order is what to copy.

1 SprintOff-GCD 2 Garrote 3 Fan of Knives 4 Rupture 5 Garrote 6 Crimson Tempest 7 Crimson Tempest 8 Rupture 9 Fan of Knives 10 Cloak of ShadowsOff-GCD 11 Crimson Vial 12 ShadowstepOff-GCD 13 Crimson Tempest 14 Envenom 15 Crimson Tempest

1 Garrote 2 Garrote 3 Fan of Knives 4 Rupture 5 Crimson Tempest 6 Crimson Tempest 7 Rupture 8 Crimson Tempest 9 Crimson Tempest 10 EvasionOff-GCD 11 SprintOff-GCD 12 Envenom 13 Light's PotentialOff-GCD 14 Voracious Heart of Ula'tekOff-GCD 15 Deathmark

1 FeintOff-GCD 2 Garrote 3 Fan of Knives 4 Rupture 5 Garrote 6 Crimson Tempest 7 Envenom 8 Crimson Tempest 9 FeintOff-GCD 10 Envenom 11 Crimson Tempest 12 Envenom 13 Light's PotentialOff-GCD 14 Voracious Heart of Ula'tekOff-GCD

The Patch 12.1 Omnium Folio has five rune rows. This is what the sampled top logs actually run in each row, read from the runes' own damage, healing and buff traces. Bold = most picked. Rows 1 and 5 are procs, so their share is inferred from the traces they leave.

Row	Raid	Mythic+
Row 1	Rune of Unleashed Fire 97%	Rune of Unleashed Fire 95% Rune of Void-Touched Orbs 5%
Row 2	Rune of Self-Mending 71% Rune of Void-Tainted Shell 5%	Rune of Self-Mending 60% Rune of Void-Tainted Shell 32% Rune of Lynxlike Reflexes 8%
Row 3	Rune of Lingering 100%	Rune of Lingering 100%
Row 4	Rune of Critical Power 55% Rune of Burning Haste 24% Rune of Masterful Cunning 18%	Rune of Critical Power 55% Rune of Masterful Cunning 32% Rune of Burning Haste 12%
Row 5	Rune of Overload 92% Rune of Echoes 8%	Rune of Overload 80% Rune of Echoes 20%

The GearInsight addon shows the same table next to your own current runes and can switch every row to the recommended one in one click.

Collected from public Patch 12.1 guides and checked for this patch. Spell names follow the language you selected on this site and must match your game client. If a macro does not work on your client, report it with the button on the card.

#showtooltip Deathmark
/cast Deathmark
/use 13

#showtooltip
/cast [@focus,harm,nodead][] Kick

#showtooltip Shadowstep
/cast [@mouseover,nodead,exists][] Shadowstep

#showtooltip
/cast [@NAME][] Tricks of the Trade

Keybinds are personal — this is not a layout to copy wholesale. What it does say is which abilities you press most, measured from the same top parses above: the more often an ability is cast, the less effort its key should take. Interrupts, defensives and movement are deliberately left out; they barely register in cast data yet must always be within reach, so choose those yourself.

Rows marked Passive are not pressed at all — they fire on their own (auto-attacks, procs) and get no key, even though they top the casts-per-minute table.

Key	Ability	Top-player CPM
1	Mutilate	20.2
2	Envenom	12.8
3	Fan of Knives	9.9
4	Crimson Tempest	6.3
5	Garrote	3.0
Z	Rupture	2.4
X	FeintOff-GCD	2.2
C	Kingsbane	1.0
V	Thistle TeaOff-GCD	1.0
R	ShadowstepOff-GCD	0.7
F	Crimson Vial	0.7
T	Deathmark	0.6
G	VanishOff-GCD	0.6
Shift+1	Thistle TeaOff-GCD	0.6
Shift+2	Tricks of the Trade	0.5
Shift+3	SprintOff-GCD	0.4