Warlock Destruction Rotation & Opener

First ~12 casts of actual top-ranked kills. Trinkets and racials vary by setup; the skill order is what to copy.

1 Conflagrate 2 Big Red RaysOff-GCD 3 Summon Infernal 4 Malevolence 5 Light's PotentialOff-GCD 6 Freightrunner's FlaskOff-GCD 7 Chaos Bolt 8 Chaos Bolt 9 Conflagrate 10 Chaos Bolt 11 Incinerate 12 Conflagrate 13 Chaos Bolt 14 Incinerate 15 Chaos Bolt

1 Incinerate 2 Wither 3 Wither 4 Summon Infernal 5 Freightrunner's FlaskOff-GCD 6 Malevolence 7 Havoc 8 Light's PotentialOff-GCD 9 Conflagrate 10 Chaos Bolt 11 Chaos Bolt 12 Conflagrate 13 Chaos Bolt 14 Soul Fire 15 Shadowburn

1 Soul Fire 2 Summon Infernal 3 Empowering VenomOff-GCD 4 Light's PotentialOff-GCD 5 Malevolence 6 Chaos Bolt 7 Conflagrate 8 Chaos Bolt 9 Conflagrate 10 Chaos Bolt 11 Incinerate 12 Chaos Bolt 13 Conflagrate 14 Chaos Bolt 15 Shadowburn

#showtooltip Conflagrate
/use 13
/use 14
/cast Big Red Rays
/cast Conflagrate

Ability	Top-player CPM
Chaos Bolt	11.1
Incinerate	10.8
Shadowburn	10.1
Conflagrate	8.4
Wither	4.1
Havoc	1.8
Soul Fire	1.2
Malevolence	1.0
Summon Infernal	0.7
Dark PactOff-GCD	0.7
Burning Rush	0.6

CPM = median casts per minute across the sampled top kills. If you're far below on a core ability, that's usually the first thing to fix.

First ~12 casts after the pull starts, taken from actual top key runs: the AoE opener is the first pack of the run, the single-target opener is the first boss. Trinkets and racials vary by setup; the skill order is what to copy.

1 Conflagrate 2 Demonic Gateway 3 Immolate 4 Curse of Tongues 5 Dark PactOff-GCD 6 Unending ResolveOff-GCD 7 Conflagrate 8 Blight of Tongues 9 Summon Infernal 10 Cataclysm 11 Lake of FireOff-GCD 12 Lake of FireOff-GCD 13 Lake of FireOff-GCD 14 Conflagrate 15 Lake of FireOff-GCD

1 Immolate 2 Conflagrate 3 Burning Rush 4 Dark PactOff-GCD 5 Immolate 6 Conflagrate 7 Incinerate 8 Light's PotentialOff-GCD 9 Rain of Fire 10 Summon Infernal 11 Empowering VenomOff-GCD 12 Cataclysm 13 Lake of FireOff-GCD 14 Lake of FireOff-GCD 15 Lake of FireOff-GCD

1 Conflagrate 2 Conflagrate 3 Immolate 4 Summon Infernal 5 Light's PotentialOff-GCD 6 Freightrunner's FlaskOff-GCD 7 Rain of Fire 8 Spell LockOff-GCD 9 Cataclysm 10 Lake of FireOff-GCD 11 Lake of FireOff-GCD 12 Lake of FireOff-GCD 13 Lake of FireOff-GCD 14 Lake of FireOff-GCD 15 Lake of FireOff-GCD

#showtooltip Conflagrate
/use 13
/use 14
/cast Spell Lock
/cast Conflagrate

The Patch 12.1 Omnium Folio has five rune rows. This is what the sampled top logs actually run in each row, read from the runes' own damage, healing and buff traces. Bold = most picked. Rows 1 and 5 are procs, so their share is inferred from the traces they leave.

Row	Raid	Mythic+
Row 1	Rune of Unleashed Fire 100%	Rune of Unleashed Fire 90% Rune of Void-Touched Orbs 10%
Row 2	Rune of Self-Mending 71% Rune of Void-Tainted Shell 3%	Rune of Self-Mending 62% Rune of Void-Tainted Shell 35% Rune of Lynxlike Reflexes 2%
Row 3	Rune of Lingering 100%	Rune of Lingering 100%
Row 4	Rune of Critical Power 68% Rune of Masterful Cunning 26% Rune of Burning Haste 5%	Rune of Critical Power 78% Rune of Burning Haste 20% Rune of Masterful Cunning 2%
Row 5	Rune of Overload 92% Rune of Echoes 8%	Rune of Overload 95% Rune of Echoes 5%

The GearInsight addon shows the same table next to your own current runes and can switch every row to the recommended one in one click.

Collected from public Patch 12.1 guides and checked for this patch. Spell names follow the language you selected on this site and must match your game client. If a macro does not work on your client, report it with the button on the card.

#showtooltip
/cast [@mouseover,harm] Havoc; [harm] Havoc

#showtooltip
/cast [@cursor] Rain of Fire

#showtooltip
/cast [@cursor] Cataclysm

#showtooltip
/cast [known:Shadowburn,@mouseover,harm] Shadowburn; [known:Shadowburn,harm] Shadowburn

#showtooltip Corruption
/use [@mouseover,harm,nodead][harm] Corruption

#showtooltip Banish
/use [mod:shift,@focus][] Banish

#showtooltip Soulstone
/target [@mouseover] Soulstone
/use Soulstone
/targetlasttarget

#showtooltip
/stopcasting
/use [mod:shift] Demonic Circle(Summon); [nomod] Demonic Circle: Teleport(Teleport)

#showtooltip
/use [known:Shadowfury,@cursor] Shadowfury; [known:Howl of Terror] Howl of Terror

/petattack

Keybinds are personal — this is not a layout to copy wholesale. What it does say is which abilities you press most, measured from the same top parses above: the more often an ability is cast, the less effort its key should take. Interrupts, defensives and movement are deliberately left out; they barely register in cast data yet must always be within reach, so choose those yourself.

Rows marked Passive are not pressed at all — they fire on their own (auto-attacks, procs) and get no key, even though they top the casts-per-minute table.

Key	Ability	Top-player CPM
1	Chaos Bolt	11.1
2	Incinerate	10.8
3	Shadowburn	10.1
4	Lake of FireOff-GCD	8.6
5	Conflagrate	8.4
Z	Rain of Fire	4.3
X	Wither	4.1
C	Immolate	2.1
V	Havoc	1.8
R	Cataclysm	1.4
F	Soul Fire	1.2
T	Ruination	1.2
G	Malevolence	1.0
Shift+1	Summon Infernal	0.7
Shift+2	Dark PactOff-GCD	0.7
Shift+3	Burning Rush	0.6
Shift+4	Curse of Tongues	0.6
Shift+5	SoulburnOff-GCD	0.4